McComb station is a train station in McComb, Mississippi, United States, serving Amtrak's City of New Orleans passenger train.

On May 30, 2021, the station building fell victim to arson and was believed to be a total loss.

[2] However, after the structure was inspected by an architectural firm, as well as two construction contractors experienced in rehabilitating burned structures, it was determined in November, 2021, that most of the depot's walls could be saved in the central area and southern ends of the building.

On January 3, 2022, Pike Construction of Mississippi began the rebuilding process, which is expected to take 9-12 months to complete.

The station was built in 1901 by the Illinois Central Railroad and was restored in 1998, and again on June 13, 2003.