912718440ENSG00000099957ENSMUSG00000022758O15547O54803NM_001394691NM_001394692NM_001394693NM_001394694NM_001394695NM_001394696NM_001394697NM_001159561NM_011028NP_001153026NP_005437NP_001336803NP_001336804NP_001336805NP_001153033NP_035158P2X purinoceptor 6 is a protein that in humans is encoded by the P2RX6 gene.

[5][6][7][8] The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations.

This gene is predominantly expressed in skeletal muscle, and regulated by p53.

The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.

[8] This article incorporates text from the United States National Library of Medicine, which is in the public domain.