Its closest rapid transit station is Phra Nang Klao Bridge MRT station on the MRT Purple Line.

[1] Initially, Nonthaburi Province had no hospital of its own and patients had to go into Bangkok (Phra Nakhon) or Thonburi to access healthcare.

Even so, hospital use did not gain popularity due to the low amount of staff present.

In 1987, after rapid economic development into the province, and the construction of Rattanathibet Road, the hospital was gradually expanded.

[2] Phra Nang Klao Hospital is used as a clinical teaching site for medical students of the School of Medicine, Siam University since January 2016.