Rasi Salai (ราษีไศล, pronounced [rāː.sǐː sā.lǎj]) is a district (amphoe) in the northern part of Sisaket province, northeastern Thailand.

Neighboring districts are (from the north clockwise): Phanom Phrai of Roi Et province; Sila Lat of Sisaket Province; Maha Chana Chai and Kho Wang of Yasothon province; Yang Chum Noi, Mueang Sisaket, Uthumphon Phisai, and Bueng Bun of Sisaket; and Rattanaburi of Surin province.

[1] The Rasi Salai Dam was built here in 1994 and unofficially decommissioned in July 2000 following devastation of local farming villages as documented by Living River Siam.

[2] The district is divided into 13 sub-districts (tambons), which are further subdivided into 190 villages (mubans).

Missing numbers are tambons which now form Sila Lat District.