tert-Butylthiol, also known as tert-butyl mercaptan (TBM), and abbreciated t-BuSH, is an organosulfur compound with the formula (CH3)3CSH.

The compound was later prepared by the reaction of the Grignard reagent, t-BuMgCl, with sulfur to give the corresponding thiolate, followed by hydrolysis.

[3] This preparation is shown below: It is made industrially by the reaction of isobutylene with hydrogen sulfide over a clay (silica alumina) catalyst.

[4] tert-Butylthiol is deprotonated by lithium hydride in an aprotic solvent such as hexamethylphosphoramide (HMPA).

tert-Butylthiol had been listed on the European Food Safety Authority (FL-no: 12.174) as a flavor additive.