The pair experiment on students in the school basement, hoping to discover the secret of reanimating corpses in a matter akin to the work of the fictional mad scientist, Victor Frankenstein.
Their hopes are soon answered when they discover a solution of Monami's blood holds the properties to bring life to dead body parts and inanimate objects.
The story begins to unfold after Mizushima carelessly accepts a honmei choco spiked with Monami's blood, turning him into a half vampire.
Her premature death leads to her father using the blood solution to transform her into a vicious Frankenstein's monster determined to get revenge against Monami.
Monami ultimately kills her archrival by ripping the flesh off the latter's body using droplets of her own blood to form spikes and impaling her skeletal corpse on top of Tokyo Tower.