West Branch Run flows through a valley known as California Hollow, which is listed as a "locally significant site" on the Columbia County Natural Areas Inventory.

West Branch Run begins in Jordan Township, Lycoming County and flows southwest for more than a mile.

[3] At the end of the valley, it receives Shingle Run, its only named tributary, and abruptly turns south.

After more than a mile, West Branch Run passes the Shoemaker Covered Bridge, crossing Pennsylvania Route 442 on the way, and turns southeast.

[2] West Branch Run joins Little Fishing Creek 11.16 miles (17.96 km) upstream of its mouth.

[2] West Branch Run flows through a valley known as California Hollow in Pine Township, Columbia County.

[7] California Hollow, which West Branch Run flows through, is listed as a "locally significant site" on the Columbia County Natural Areas Inventory.