Wobble base pair

[1] The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C).

Wobble base pairs are fundamental in RNA secondary structure and are critical for the proper translation of the genetic code.

For translation, each of these codons requires a tRNA molecule with an anticodon with which it can stably complement.

[4] Crick creatively named it for the small amount of "play" or wobble that occurs at this third codon position.

[7] These notions led Francis Crick to the creation of the wobble hypothesis, a set of four relationships explaining these naturally occurring attributes.

These aminoacylated tRNAs go on to the translation of an mRNA transcript, and are the fundamental elements that connect to the codon of the amino acid.