In fall 1814, the European powers at the Congress of Vienna decided that the Republic of Genoa would not be reestablished and its territory given to the Kingdom of Sardinia.

On 7 January 1815, the British occupation forces in Genoa handed control of the city to the Piedmontese General Ignazio Thaon di Revel.

In 1859, the regiment participated in the Second Italian War of Independence and the following year in the Sardinian campaign in central and southern Italy.

During World War II, the regiment was assigned to the 55th Infantry Division "Savona", with which it was deployed to Libya for the Western Desert Campaign.

[1] In 1975, the regiment's flag and traditions were assigned to the 16th Infantry Battalion "Savona", which trained recruits destined for the Armored Division "Ariete".

[1][3][4][5] The brigade was assigned the provinces of Tortona, Savona, Albenga, Genoa, Chiavari, Novi, Levante, Voghera, and Bobbio as recruiting zone.

[1][3][4][5] After returning from exile King Victor Emmanuel I abolished all the freedoms granted by the Napoleonic Code and established a fiercely oppressive rule.

[1][3][4][5] On 31 May 1821, the four infantry brigades, which had sided with the revolutionaries, were stricken from the rolls of the Royal Sardinian Army and their personnel dismissed from service, while the troops of the regiments, who had not participated in the revolt, were assigned to four provisional line battalions.

On 23 March 1849, after being defeated in the Battle of Novara, King Charles Albert abdicated in favour of his son Victor Emmanuel.

On 24 March, the new king met with the Austrian Field Marshal Radetzky at Vignale and agreed to an armistice, which ended the First Italian War of Independence.

[1][3] In 1855, the Cholera pandemic of 1854-55 arrived in the Kingdom of Sardinia and the troops of the 16th Infantry Regiment were assigned to the hospitals in Genoa to support the medical staff.

On 5 May 1860, Giuseppe Garibaldi's Expedition of the Thousand set off, with the support of the Sardinian government, from Genoa and landed on 11 May in Marsala in Sicily.

The brigade crossed the Dottori canal and occupied Polazzo at the foot of the Karst plateau, which blocked the way to the city of Trieste.

For the rest of the year the Brigade "Savona" participated in the Italian attempts to dislodge the Austro-Hungarian forces from the slopes and hills of the Karst plateau.

From 23 June to 7 July 1915, during the First Battle of the Isonzo, the brigade attacked the first Austro-Hungarian line Southeast of Polazzo and suffered more than 1,900 casualties for little gain.

[1][6][8] At the end of January 1916, also the 16th Infantry Regiment arrived in Albania, where in early February the Austro-Hungarian forces began an offensive towards Durrës.

On 23 February the Brigade "Savona" fell back to Durrës leaving the II Battalion of the 15th Infantry Regiment behind to fight to annihilation as rearguard.

On 26 February 1916, the remaining troops of the brigade were evacuated from Durrës and the next day they arrived again in Vlorë to establish a new defensive line around this important port city in the South of Albania.

By May 1916, the Italian XVI Corps in the area had grown to some 100,000 men and for the rest of 1916 and all of 1917 the front along the Vjosa river in Southern Albania became static with neither side willing to go on the offensive.

After a short break the Italian units fell back to the hills South of the river, where they defeated heavy Austro-Hungarian counterattacks on 22 and 25 August 1918.

[1][6][9] After the war the 16th Infantry Regiment was awarded a Silver Medal of Military Valor for its conduct at Polazzo in 1915, in Durrës in 1916, and on the Seman river in 1918, while the 15th Infantry Regiment was awarded a Bronze Medal of Military Valor for its conduct at Polazzo and on Monte Sei Busi 1915.

From 4 November 1935, the division was stationed in the Adigrat and in December 1935 it fought in the Ādī K’edawīt - Doghea pass area.

From 10-25 June 1940, during the Italian invasion of France, the "Savona" division deployed along the French Tunisian-Italian Libyan border.

[1][13][15] In September 1940, during the Italian invasion of Egypt, and in December 1940, during the British Operation Compass counteroffensive, the "Savona" division remained at its bases.

Only in June 1941, the division joined the Western Desert campaign and moved East to participate in the Siege of Tobruk.

[1][13][15] On 18 November 1941, the British Eighth Army began Operation Crusader and attacked Axis positions from Bi’r Qirbah to Halfaya.

On 4 December 1941, as the Afrika Korps prepared to retreat to the Gazala Line, the "Savona" division was ordered to cover the Axis withdrawal by tying up British forces in the Bardia—Sollum—Halfaya sector for as long as possible.

During the rest of the month the "Savona" division's supply situation deteriorated, with food, water and ammunition becoming scarce.

Already on 14 March 1977 the President of the Italian Republic Giovanni Leone had issued decree 173, which assigned the flag and traditions of the 5th Bersaglieri Regiment to the new battalion.

Consequently the Armored Division "Ariete" was disbanded on 1 October 1986 and the 16th Infantry Battalion "Savona" was transferred to the Northwestern Military Region.