The 2004–05 Quaid-e-Azam Trophy was one of two first-class domestic cricket competitions that were held in Pakistan during the 2004–05 season.

It was the first edition of the Quaid-e-Azam Trophy under a new sponsorship agreement with ABN AMRO signed by the Pakistan Cricket Board.

[1] The competition was organised as a round-robin qualifying group stage of four-day matches, with the top two teams contesting a five-day final.

[2][3] Peshawar won the trophy for the second time on the basis of having taken a first-innings lead in the final after the match against Faisalabad resulted in a draw when rain reduced play to just 28 overs during the final two days.

[4][5][6] The top two teams in the round-robin group stage (highlighted) advanced to the final.