The 2010 Bancolombia Open is a professional tennis tournament played on indoor red clay courts.

It is part of the 2010 ATP Challenger Tour.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: João Souza def.

Alejandro Falla, 4–6, 6–4, 6–1 Franco Ferreiro / Santiago González def.

Dominik Meffert / Philipp Oswald, 6–3, 5–7, [10–7]