The 2010 Open d'Orléans was a professional tennis tournament played on hard courts.

It was the sixth edition of the tournament which was part of the 2010 ATP Challenger Tour.

The following players received wildcards into the singles main draw: The following players received a special entrant into the singles main draw: The following players received entry from the qualifying draw: Nicolas Mahut def.

Grigor Dimitrov, 2–6, 7–6(6), 7–6(4) Pierre-Hugues Herbert / Nicolas Renavand def.

Sébastien Grosjean / Nicolas Mahut, 7–6(3), 1–6, [10–6]