The 2010 Copa Petrobras Buenos Aires was a professional tennis tournament played on red clay courts.

It was the seventh edition of the tournament which was part of the 2010 ATP Challenger Tour.

It took place in Buenos Aires, Argentina between 4 and 11 October 2010.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: Máximo González def.

Pablo Cuevas, 6–4, 6–3 Carlos Berlocq / Brian Dabul def.