[6][7] Eighteen teams took part in the league in this season: the sixteen teams from the previous season, plus the 2019 Primera B champions Santiago Wanderers and Deportes La Serena, winners of the Primera B promotion play-offs.

[57] On 8 June, ANFP's Council of Presidents decided to resume the league on 31 July with matches to be played behind closed doors and clubs having at least four weeks of training sessions, pending approval from the Chilean government.

[59] On 19 August, in a press conference held at Estadio Nacional Julio Martínez Prádanos in Santiago, Chilean President Sebastián Piñera confirmed 29 August as the date of resumption of both the first and second tier seasons, with games to be played behind closed doors.

[60] On 26 September the match between Colo-Colo and Deportes Antofagasta, scheduled to be played on that day at 11:00, was suspended due to the discovery of a positive COVID-19 case in the former team following their return from Brazil where they played a Copa Libertadores group stage match against Athletico Paranaense.

[62] On 11 December, the ANFP announced the suspension of the Round 23 matches between Universidad de Chile and Deportes Iquique and between Unión La Calera and O'Higgins due to positive cases for COVID-19 being reported in Deportes Iquique and Unión La Calera.