2021–22 Djibouti Premier League

[1] The 20,000-capacity El Hadj Hassan Gouled Aptidon Stadium is the main venue of the league.

Arta/Solar7, captained by former FC Barcelona midfielder Alex Song, won the league for the second consecutive season.

[2] The team's forward, Gabriel Dadzie, won the Golden Boot award, scoring 18 goals.

[3] The two newly promoted teams, EAD/PK 12 and Arhiba FC, were both relegated.

Arhiba lost every game while EAD / PK 12 finished 9th on goal difference after a 0–1 loss to FC Dikhil in their final match.