The 2021–22 FA Vase (Known for sponsorship reasons as the Buildbase FA Vase) was the 48th season of the FA Vase, an annual football competition for teams playing in Levels 9 and 10 (steps 5 & 6) of the English National League System.
All ties this season were played to a finish on the day.
For this season there were no replays in any of the rounds to minimise fixture congestion due to late start of the football season brought about by the COVID-19 pandemic.
If games finished level after 90 minutes, the match was decided by penalties to find the winner of the tie, apart from the Final where there were 30 minutes extra time (15 minutes each way) followed by penalties if still level after the extra time period.
The draw was made on 25 October 2021 featuring the 105 winners from the previous round with an additional 23 teams joining.