The 2021 Campeonato Brasileiro Série C was a football competition held in Brazil, equivalent to the third division.
[1] Twenty teams competed in the tournament, twelve returning from the 2020 season, four promoted from the 2020 Campeonato Brasileiro Série D (Altos, Floresta, Mirassol and Novorizontino)[2] and four relegated from the 2020 Campeonato Brasileiro Série B (Botafogo-SP, Figueirense, Oeste and Paraná).
[3] Criciúma, Ituano, Novorizontino and Tombense were promoted to the 2022 Campeonato Brasileiro Série B.
[4] Ituano defeated Tombense 4–1 on aggregate in the finals to win their second title.
If tied on points, the criteria to determine the ranking would be the same as used in the first stage (Regulations Article 19).
The finals were played on a home-and-away two-legged basis, with the higher-seeded team hosting the second leg.
If tied on aggregate, the away goals rule would not be used, extra time would not be played, and the penalty shoot-out would be used to determine the champions (Regulations Article 20).
Draw in the headquarters of the Brazilian Football Confederation (Regulations Article 21).