Mozart Santos (10 June to 30 July) The 2021 season was the 100th in the Cruzeiro Esporte Clube's existence.

Along with the Campeonato Brasileiro Série B, the club also competed in the Campeonato Mineiro and in the Copa do Brasil.

Source: Competitions The drawn for the first stage was held on 2 March.

[43] Players with no appearances not included in the list.

Includes all competitive matches.