In September 1863, a detachment from Company H of the 43rd Regiment which had not been captured at Vicksburg was organized as Captain Merriman Pound's Battalion Mississippi Sharpshooters and sent to join Braxton Bragg's Army of the Tennessee in Georgia, fighting at the Battle of Chickamauga.

After Chickamauga, Pound's Battalion was sent back to Mississippi and some of the 43rd rode with General Forrest to drive Union forces out of the state.

In the spring of 1864, the 43rd regiment was sent to Georgia to fight in the Atlanta Campaign against William T. Sherman's invading Federal army.

After Atlanta was lost, the 43rd fought in General John Bell Hood's Tennessee Campaign which included the Battles of Franklin and Nashville.

The 43rd Mississippi was part of Gen. Joseph E. Johnston's surrender of the Army of Tennessee at Bennett Place on April 26, 1865.