1109530806ENSG00000134917ENSMUSG00000031994Q9UP79P57110NM_007037NM_013906NM_001326292NP_008968NP_038934.2A disintegrin and metalloproteinase with thrombospondin motifs 8 is an enzyme that in humans is encoded by the ADAMTS8 gene.

[5][6] This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.

The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo.

[6] A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

[6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.