81792239337ENSG00000151388ENSG00000281690ENSMUSG00000047497P58397Q811B3NM_030955NM_001324511NM_001324512NM_175501NP_001311440NP_001311441NP_112217NP_780710A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene.

[5] This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.

Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif.

It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

This article on a gene on human chromosome 5 is a stub.