[1] The street is named for James Hamilton, 6th Earl of Abercorn, a financial benefactor of the Georgia colony.

They are (from north to south): For five blocks between and Oglethorpe and Lafayette Squares, Abercorn Street forms the western boundary of Colonial Park Cemetery,[4] which was established in 1750 (275 years ago) (1750).

From north to south:[5] John Houstoun, Savannah's first mayor, lived in the Houston–Johnson–Screven House, at 32 Abercorn Street, which was built around 1784.

Within a few blocks, the restrained architecture of the historic district gave way to late-Victorian flights of fancy — big old wooden houses with romantic towers, gables, and elaborate gingerbread trim.

A celebration of the life of The Lady Chablis took place at the Lucas Theatre on Abercorn Street in November 2016, following her death two months earlier.