Oglethorpe Avenue is a prominent street in Savannah, Georgia, United States.

The street is named for the founder of the Savannah colony, James Edward Oglethorpe.

[2] It contains what is believed to be the two oldest extant buildings in the city: Eppinger House and the Christian Camphor Cottage.

A memorial in the median of Oglethorpe Avenue at Bull Street lists the twenty people known to be interred in a Jewish cemetery, today known as Bull Street Cemetery, which formerly stood there.

[4] Below is a selection of notable buildings and structures on Oglethorpe Avenue, all in Savannah's Historic District.