The street is named for Sir John Barnard, Lord Mayor of London in 1737 and 1740.

[1] Its northern section passes through the Savannah Historic District, a National Historic Landmark District.

[2] Barnard Street goes around five of Savannah's 22 squares.

They are (from north to south): Below is a selection of notable buildings and structures on Barnard Street, all in Savannah's Historic District.

From north to south:[3] The Bulloch–Habersham House stood on Barnard Street, in the southwestern trust lot of Orleans Square, at the corner of West Perry Street, in the 19th and early 20th centuries.