Located south of Gordon Street, it runs for about 0.77 miles (1.24 km) from Martin Luther King Jr. Boulevard in the west to East Broad Street in the east.

Originally known only as Gaston Street singular, its addresses are now split between "West Gaston Street" and "East Gaston Street", the transition occurring at Bull Street in the center of the downtown area.

Named for William Gaston, a prominent Savannahian merchant,[1] the street is entirely within Savannah Historic District, a National Historic Landmark District.

The acronym NOG (North of Gaston) is used colloquially to separate two distinct parts of Savannah: the historic section, from the Savannah River to the northern edge of Forsyth Park, and the less desirable part to the south of Gaston Street.

[3][4] Below is a selection of notable buildings and structures on Gaston Street, all in Savannah's Historic District.