To solve the liquid storage problem, scientists at Oak Ridge National Laboratory devised a synthesis to turn liquid americium–acid solution into a precipitated form of americium for safer handling and more efficient storage.

When decomposition begins to occur, the oxalate will turn into the desired black americium dioxide; to ensure no oxalate remains in the newly forming dioxide, the oven temperature is increased and held at 800 °C (1,470 °F) then slowly allowed to cool to room temperature.

In the late 2010s, americium dioxide has been of interest to ESA as power source for radioisotope thermoelectric generators (RTGs) for deep space exploration spacecraft and satellites.

It is based on the same principles as the historic production method developed at Oak Ridge National Laboratory.

[5] Americium-aluminium alloys can be formed by melting americium dioxide with aluminium and an additional fluxing agent.