It is part of Northeastern Pennsylvania and is located 28 miles (45 km) southwest of Wilkes-Barre.

[4] It is one of the two principal communities of the Bloomsburg–Berwick metropolitan area, which covers Columbia and Montour counties,[5] and had a combined population of 85,562 at the 2010 census.

Situated on the north bank of the Susquehanna River, the borough was first settled in 1769, founded in 1786, and incorporated in 1818.

[7] Santa Claus is present every year to serve Berwick's famous Wise Potato Chips to everyone who drives past him.

The Berwick Armory and Jackson Mansion and Carriage House are listed on the National Register of Historic Places.

[11] In the other direction, PA 93 splits west from US 11 as Orange Street and leads 10 miles (16 km) to Orangeville.

The Berwick area had a large influx of immigrants approximately between 1890 and 1920, which had a great impact on the current population that continues to this day.

The American Car & Foundry plant was also a producer of rolling stock for railroads.

The borough is home to Berwick Offray, a gift ribbon manufacturing division of CSS Industries, and Wise Foods, a snack food company founded by Berwick native Earl Wise in the first half of the twentieth century, famous for its potato chips.

Holy Family also offers C.C.D[24][25] Berwick is home to a dedicated campus of Luzerne County Community College, located in the Eagles Building.

The Roman Catholic Diocese of Harrisburg operates Holy Family Consolidated School.