Big Creek is a 221-mile (356 km) stream in the central Great Plains of North America.

It is a tributary of the Smoky Hill River, and the entirety of its length lies in the U.S. state of Kansas.

[2] Big Creek originates in the High Plains of northwestern Kansas.

[3] Its source lies in extreme northwestern Gove County.

[3] In Ellis, it is dammed to maintain a small reservoir, Big Creek Lake.