In molecular biology, binding domain is a protein domain which binds to a specific atom or molecule, such as calcium or DNA.
A protein domain is a part of a protein sequence and a tertiary structure that can change or evolve, function, and live by itself independent of the rest of the protein chain.
[1] Upon binding, proteins may undergo a conformational change.
Binding domains are essential for the function of many proteins.
They are essential because they help splice, assemble, and translate proteins.