The storyline led Kaine to reclaim the heroic Scarlet Spider mantle and appear in his own comic book series.

This storyline details Jackal resurfacing as he manages to get Rhino, Lizard, Doctor Octopus and a female Electro on his side with a chance to reunite with their loved ones.

Approaching several of Spider-Man's enemies, Jackal offers a deal to them in the form of the chance to revive their lost loved ones if they follow his orders.

Before continuing, Martha Connors informs Jackal about the fire in Edmond, Oklahoma and watches the news to see Spider-Man's arrival as none of them had any involvement with the incident.

[8] When Peter Parker scanned Living Brain to find out why it was acting unusually, Doctor Octopus' consciousness asked why it was erased.

After attending J. Jonah Jameson Sr.'s funeral, Peter decides to pay Jerry Salteres a visit in order to investigate why his spider-sense went off in his presence.

When they reach his house, his wife Emma reveals that New U had mysteriously taken Jerry away after he had accidentally forgotten to take a post-procedure daily pill prescribed by New U and his health decayed.

Spider-Man delves deep into the laboratory and discovers several stasis tubes, with one of them apparently containing nothing but Jerry's nervous system, completely stripped off his body, and alive.

The Jackal claims that this one is not a clone, but the real Gwen who was harvested from her remains and still remembers everything in her life including her death (during which she was apparently aware but paralyzed by Green Goblin's gas and learned that Peter was Spider-Man).

He was shown to have made reanimations of the villains Alistair Smythe, Bart Hamilton's Green Goblin form, Big Man, Eduardo Lobo, Hitman, a Hobgoblin, a Jack O'Lantern, Kangaroo I, Massacre, Mirage, Montana, a Mysterio, Ox I, a Rose, Spencer Smythe, Stilt-Man, and Tarantula as well as reanimations of Ashley Kafka, Jean DeWolff, and Spider-Woman.

Back at Horizon University, Kaine tells Max Modell, Hector Baez, and the rest of the employees about the Carrion virus and reveals his condition.

The scientists figure they can use Kaine to try and find a cure for the virus since he is not contagious and decide to call the cops to alert them of the possible epidemic.

Jackal sends Electro and Rhino to retrieve Gwen and attends a meeting where he reveals his plan to move into Phase 2 of his project, allowing more New U Technologies factories and less government oversights.

As Doctor Octopus is working on improving the cloning process, he is told by Jackal that he also plans to move to a new location since Spider-Man knows where he is.

A flashback is shown that the Doctor Octopus-possessed Octobot went to Potter's Field where his body is buried to obtain some genetic material only to find that it was grave robbed alongside the corpses of Alistair Smythe and other villains.

After returning to the Great Web thanks to the Master Weaver, Kaine discovers that he is dying from a zombie-like Carrion virus that is a side-effect of Warren's cloning process, and is not allowed to go back to his Earth to avoid anyone catching it.

While Spider-Woman of Earth-65 changes her looks, Kaine reveals to Karn that his research on his deceased counterpart led him to discover when he is going to die and he has very limited time.

Gwen witnesses Jackal order the villains to kill Spider-Man and wants to help, but the alarm goes off and she and her father catch the Carrion virus.

Ben Reilly takes the New U pills and steals a citizen's Webware to stabilize the cells in his body and goes back to his safehouse (which is a recreation of Peter's childhood home).

Knowing how annoying it is to be stuck in the same location, Jackal assigns Prowler to take care of a potential hacker in San Francisco.

After confronting his killer Electro, Prowler figures out Madame Web's precognition and goes to Alcatraz where he sets off a trap and gets caught in the process.

[25] Cindy Moon is glad to have her family back following her trip to the Negative Zone, but still feels distant from them and does not make as much of an effort to spend as much time with them.

When J. Jonah Jameson wants one of his workers to investigate the New U scenario in San Francisco, Cindy volunteers to go to get away from the city as Hector Cervantez (now calling himself Spectro) accompanies her.

She and Hector decide to investigate Jameson's room in New U Technologies and she uses her powers to create a different costume from her Silk outfit to avoid suspicion.

Moon tells Albert that he still believes that Cindy's life would improve if he found a way to remove her powers with her mother overhearing the conversation.

Cindy gives him Rafferty and Lola's research to voice skepticism on the New U Technologies and Jameson invites her to join him on a quick trip to the facility.

Mattie tells her that she is suspicious of the whole experiment as some of the other resurrected characters have been showing slight behavioral glitches and takes her to a place called "Haven" where they find Hector back in his own body.

Moon has hidden a package that Cindy wanted Albert to open and tells Rafferty and Lola to stay out of their business while receiving instructions from a mysterious woman.

After Spider-Man sends out the Webware Emergency Signal, J. Jonah Jameson and Silk find Marla and Mattie reduced to dust.

At a local bar during the second story, Dr. Rita Clarkson unwinds from the day with a drink, but is met by a disguised and disfigured Ben Reilly.