Glycinamide

Glycinamide is an organic compound with the molecular formula H2NCH2C(O)NH2.

[1] It is a ligand for transition metals, related to amino acid complexes.

In some complexes, it binds through the amine and the carbonyl oxygen, forming a five-membered chelate ring.

Glycinamide hydrochloride has a pKa near the physiological pH (8.20 at 20°C), making it useful in cell culture work.

Its ΔpKa/°C is -0.029 and it has a solubility in water at 0 °C of 6.4 M. Glycinamide is a reagent used in the synthesis of glycineamide ribonucleotide (an intermediate in de novo purine biosynthesis).