Kabale is approximately 143 kilometres (89 mi), by road, southwest of the city of Mbarara, the largest urban centre in Uganda's Western Region.

[1] Kabale is located approximately 410 kilometres (255 mi), by road, south-west of Kampala, the capital of Uganda.

[2] Kabale sits approximately 25 kilometres (16 mi), north of the town of Katuna at the international border with Rwanda.

The Uganda Bureau of Statistics (UBOS) estimated the district population, as constituted on 1 July 2020, at 248,700.

UBOS calculated the average annual population growth rate at 1.3 percent, between 2014 and 2020.