Kamwenge District is part of the Kingdom of Toro, one of the ancient traditional monarchies in Uganda.

[2] The town of Kamwenge, where the district headquarters are located, is approximately 64 kilometres (40 mi), by road, south-east of Fort Portal, the largest city in the Toro sub-region.

Agro processing and commercial farming are the major economic activities and source of livelihood in the district.

Other crops include sorghum, millet, groundnuts, beans, tea, coffee, cotton, nuts, beans, tea, coffee, cotton, tomatoes, cabbage, onions and pineapples, which are all grown on small scale mainly for subsistence.

The coming of Congolese refugees affected cattle keepers in the area as they were displaced and had to relocate to other places within and outside the district.

Land in the refuge settlement is now used for agricultural production especially maize, beans and Irish potatoes; the area has become a business centre attracting traders from the whole country.

Similarly, the ongoing rural electrification programme targeting the entire District has increased linear settlements thus changing land use patterns to small-scale informal sector activities like welding, value addition in agriculture and other related occupations.

Other natural resources include Limestone, Gold, Tin, Marble, Sand, Clay and stone quarries.

• Railway transport: According to the NDPII (2015/16-2019/20), plans are under way to boost economic activity of Kamwenge through planned infrastructure projects like the Standard Gauge Railway Network where Kamwenge will be directly connected to Mombasa (Kenya) and Mpondwe (DRC).

The major urban centres include: Kabuga Hill is about 5 kilometres (3.1 mi) from Kamwenge town, rising about 1,581 metres (5,187 ft).