Methylthiomethyl ether

Hydroxyl groups are present in many chemical compounds and they must be protected during oxidation, acylation, halogenation, dehydration and other reactions to which they are susceptible.

They can be easily protected with MTM ethers and recovered in good yield.

The other is a special method, in which dimethyl sulfoxide (DMSO) and acetic anhydride (Ac2O) are used.

In this case, the reaction proceeds with Pummerer rearrangement: MTM ethers have another advantage.

This type of alcohol protecting group is robust under mild acidic reaction conditions.