[3][4][5] Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds.

The gene structure (number and length of exons) is similar among family members.

Multiple alternatively spliced variants that encode two isoforms have been identified for this gene.

Low sulfotransferase activity was found to be predictive to lack of response to topical minoxidil for hair re-growth.

[7] In a clinical study, a novel formula using a hypoxia mimetic pathway demonstrated to increase SULT1A1 activity in human subjects in-vivo.