Seychelles competed in the Olympic Games for the first time at the 1980 Summer Olympics in Moscow, USSR.

Nine athletes represented Seychelles in 1980.

Men's 100 metres Men's 200 metres Men's 400 metres Men's Marathon Men's 110 m Hurdles Men's 3,000 m Steeplechase Men's 4 × 100 metres Relay Men's 4 × 400 metres Relay Men's Triple Jump Women's 100 metres Women's 200 metres Women's 800 metres Women's 1,500 metres Two boxers represented Seychelles in 1980.

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