Uridine-5′-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1′ carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5′ position.

[1] UTP can be biosynthesized from UDP by Nucleoside Diphosphate Kinase after using the phosphate group from ATP.

UTP also has the role of a source of energy or an activator of substrates in metabolic reactions, like that of ATP, but more specific.

However, there is evidence from various model systems to suggest it has applications in pathogen defense and injury repair.

In mice UTP has been found to interact with P2Y4 receptors to mediate an enhancement in antibody production.