The 2021–22 Liga Națională (known as the Liga Zimbrilor) was the 64th season of the Liga Națională, Romanian premier handball league.
[1][2] Dinamo București won their eighteenth title.
[3] The following 14 clubs compete in the Liga Națională during the 2021–22 season: The 11th and 12th-placed teams of the Liga Națională faces the 3rd and 4th-placed team of the Divizia A.
The first two places promoted to Liga Națională and the last two relegated to Divizia A.
The play-offs were played on neutral ground, in Ghimbav.