The 2021 TCCB Open was a professional women's tennis tournament played on outdoor clay courts.

It was the first edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour.

It took place in Collonge-Bellerive, Switzerland between 30 August and 5 September 2021.

[1] The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: