The town of Amuria serves as the district headquarters.

The town of Amuria is located approximately 45 kilometres (28 mi) north of Soroti, the largest town in the sub-region.

The 2002 census estimated the population at 180,000.

[4] The economy of Amuria District is based on two main activities: subsistence agriculture and animal husbandry.

Over 90 percent of the population engages in either or both activities.