The hospital is located on the Kapchorwa–Suam Road, in the town of Bukwo, approximately 134 kilometres (83 mi) northeast of Mbale Regional Referral Hospital.

[1] The coordinates of Bukwo Hospital are 1°17'39.0"N, 34°45'19.0"E (Latitude: 1.294158; Longitude: 34.755286).

It was built in the 2000s, with laying of the foundation stone in June 2010.

[3] The hospital is plagued by a lack of electricity[4] and understaffing.

[5] In 2013, the government of Uganda secured a loan from the World Bank to renovate certain Ugandan hospitals, including this hospital.