It is located approximately 200 square kilometres (77 sq mi) west of Uganda's capital Kampala.

It covers an area of 1,556 square kilometres (601 sq mi)[1] and recorded a population of 177,054 in the 2014 Ugandan census.

[3] It borders the districts of Kamwenge to the northwest, Kyegegwa to the northeast, Sembabule to the east, and Kiruhura to the south, and Ibanda to the west.

[2] Historically, the economy of Kazo District revolved around the rearing of Ankole cattle by semi-nomadic pastoralists.

Major crops include beans, matooke, millet, corn, sweet potatoes and coffee.