The town of Nakasongola is the site of the district's administrative headquarters.

Nakasongola, the main municipal, administrative, and commercial center of the district, is approximately 140 kilometres (87 mi), by road, north of Kampala, the capital and largest city of Uganda.

The commission of inquiry into the local government system in 1987 recognized that Nakasongola was too far from the administrative center of Luweero to be administered directly from there.

Nakasongola suffered from relative neglect due to the distance from the then district headquarters.

[2] The district covers 4,909 square kilometres (1,895 sq mi),[3] of which 4.6% is permanent wetland.