[2][3] The town of Palenga, where the district headquarters are located is about 24 kilometres (15 mi), by road, south of Gulu, the largest city in the Acholi sub-region.

[4] This is approximately 311 kilometres (193 mi), by road, north of Kampala, the largest city and capital of Uganda.

[5] Omoro District was created by the Parliament of Uganda on 3 September 2015, and became operational on 1 July 2016.

[6] The main road from Kampala to Gulu (Kampala-Gulu Road), passes through the district in a general south to north direction.

[7] The former speaker of parliament in Uganda, Jacob Oulanyah, now deceased, concurrently served as the elected representative of Omoro District in parliament, starting back when Omoro was a county in Gulu District.