Peptide libraries are a popular tool for experiments in drug design, protein–protein interactions, and other biochemical and pharmaceutical applications.
Peptide libraries generally encompass only a fraction of this diversity, selected for depending on the needs of the experiment, for instance keeping some amino acids constant at certain positions.
[5] Biological reagent companies, such as Pepscan,[6] ProteoGenix,[7] Mimotopes,[8] GenScript and many others, manufacture customized peptide libraries.
[9] A peptide chain of 10 residues in length is used in native chemical ligation with a larger recombinantly expressed protein.
This peptide library would be useful for analyzing the effect of the post-translational modification acetylation on lysine which neutralizes the positive charge.