Schizophyllan (Sonifilan, SPG) is a neutral extracellular polysaccharide produced by the fungus Schizophyllum commune.

It is known for several things, including its ability to stimulate the immune system, carry metals in water, aid in delivering drugs, and use in some nanofibers.

[1] Schizophyllan, classified as a beta-glucan and extracted from the fungus Schizophyllum commune, showed no quantifiable adverse reactions through independent scientific procedures.

Studies have validated that 10 mg (or less) of a high quality, adequately processed chemically similar beta-glucan is a sufficient dose to elicit a measurable effect on immune cells.

In addition, small particle beta-glucans modified to prevent re-aggregation during digestion have the most positive effects on immune potentiation.