Ninoy Aquino Avenue is a north–south collector road that links Pasay and Parañaque in southern Metro Manila, Philippines.

[1] It serves as an extension to Dr. Santos Avenue (formerly Sucat Road) and a feeder road to Ninoy Aquino International Airport (NAIA) from the south and the east.

It then travels north toward the old NAIA Terminal 1, traversing Barangays La Huerta and Santo Niño.

Notable landmarks include the Dampa Seafood Market, the former Casino Filipino Airport, and Duty Free Fiestamall.

[2] Its stretch from its northern terminus at NAIA Road (formerly MIA Road) to its sharp curve in La Huerta occupies the former right-of-way of the Manila Railroad Company's Paco–Naic branch.