Gregorio Araneta Avenue is a suburban arterial road in the Santa Mesa Heights area of Quezon City, northeastern Metro Manila, Philippines.

Constructed in 1985,[1][better source needed] it is a six-to-eight-lane divided avenue designated as part of Circumferential Road 3 (C-3) and a physical continuation of Sergeant Rivera Street, which travels from Santo Domingo Avenue at its north end near Balintawak in Quezon City and meets N. Domingo Street in the south in San Juan near the border with Santa Mesa, Manila.

It was named after lawyer and landowner Gregorio S. Araneta, who owned the Santa Mesa Heights Subdivision on which it was built.

The Metro Manila Skyway Stage 3 covers almost the entire road, starting from Sergeant Rivera Avenue and ending at the San Juan River.

The oldest is Funeraria Nacional, which moved to Gregorio Araneta from its old address in downtown Avenida Rizal in 1968 and is now affiliated with Heritage Park after an extensive renovation.