Lacson Avenue is the principal northwest–southeast artery in the Sampaloc district in northern Manila, Philippines.

It is a 6-8 lane median divided avenue that runs approximately 2.9 kilometers (1.8 mi) from Tayuman Street in Santa Cruz to Nagtahan Interchange.

It then widens as it crosses Tayuman and Consuelo Streets across SM City San Lazaro.

The road then intersects with Dimasalang Street and España Boulevard in Sampaloc, passing the University of Santo Tomas campus.

Nagtahan Bridge was renamed to Mabini Bridge in 1967,[1] while in 1971, Governor Forbes Street was renamed Arsenio H. Lacson Street after the former Manila mayor who served from 1952 to 1962.