Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with the GRAM domain.

Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bi-phosphate.

[2] Mutations in gene encoding myotubularin-related proteins have been associated with disease.

[3]